Jackson-Weiss Syndrome (JWS) is a rare genetic disorder characterized by foot abnormalities. Symtoms include abnormally broad big toes and/or malformation or fusion of certain bones within the feet.

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| About 60-70% of people with diabetes have mild to severe forms of diabetic nerve damage, which in severe forms can lead to lower limb amputations. Approximately 56,000 people a year lose their foot or leg to diabetes. |
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